{"id":9443,"date":"2025-09-15T15:49:52","date_gmt":"2025-09-15T13:49:52","guid":{"rendered":"https:\/\/rvh-synergie.org\/actualites\/les-chercheurs-identifient-le-lien-entre-le-folate-excessif-et-le-diabete-gestationnel\/"},"modified":"2025-09-15T15:49:58","modified_gmt":"2025-09-15T13:49:58","slug":"les-chercheurs-identifient-le-lien-entre-le-folate-excessif-et-le-diabete-gestationnel","status":"publish","type":"post","link":"https:\/\/rvh-synergie.org\/actualites\/les-chercheurs-identifient-le-lien-entre-le-folate-excessif-et-le-diabete-gestationnel\/","title":{"rendered":"Les chercheurs identifient le lien entre le folate excessif et le diab\u00e8te gestationnel"},"content":{"rendered":"
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Une consommation ad\u00e9quate de folates est recommand\u00e9e pour les femmes en pr\u00e9conception et en grossesse pour assurer la croissance et le d\u00e9veloppement cellulaires. Mais de nouvelles recherches de l’Universit\u00e9 d’Ad\u00e9la\u00efde et de l’Universit\u00e9 Flinders ont r\u00e9v\u00e9l\u00e9 la n\u00e9cessit\u00e9 d’\u00e9tablir une limite sup\u00e9rieure s\u00fbre de consommation.<\/p>\n

Les lignes directrices actuelles recommandent une suppl\u00e9mentation en 400 \u00e0 500 microgrammes (\u00b5g) d’acide folique quotidiennement, commen\u00e7ant au moins un mois avant la conception et se poursuivant au cours du premier trimestre, pour r\u00e9duire le risque de d\u00e9fauts du tube neural tels que le spina bifida.<\/p>\n

Le Dr Tanja Jankovic-Karasoulos, de l’\u00c9cole de biomedecine et du Robinson de Robinson Institute de l’universit\u00e9, a trouv\u00e9 un exc\u00e8s de niveaux de folate maternelle – utilis\u00e9s par le double impact de la fortification alimentaire de l’acide folique (FA) et des doses de diab\u00e9tes gestationnelles plus \u00e9lev\u00e9es (GDM).<\/p>\n

Les niveaux de folate de plus de 2 000 femmes pr\u00e9 -formiti\u00e8res et post-fortification ont \u00e9t\u00e9 analys\u00e9s \u00e0 l’Universit\u00e9 Flinders dans le cadre de l’\u00e9tude, qui a \u00e9t\u00e9 publi\u00e9e dans la revue Nutriments<\/i>.<\/p>\n

\u00ab\u00a0Notre \u00e9tude montre que l’exc\u00e8s de folate maternelle augmente consid\u00e9rablement le risque de GDM dans notre cohorte de grossesse post-fortification\u00a0\u00bb, explique le Dr Jankovic-Karasoulos.<\/p>\n

\u00ab\u00a0Nous soup\u00e7onnons qu’une augmentation de l’apport en AF au cours des 10 \u00e0 15 derni\u00e8res ann\u00e9es contribue \u00e0 l’augmentation constante de la pr\u00e9valence du GDM en Australie.\u00a0\u00bb<\/p>\n

L’incidence du diab\u00e8te gestationnel en Australie a plus que tripl\u00e9 de 5,6% des femmes en 2010 \u00e0 19,3% en 2022.<\/p>\n

\u00ab\u00a0Le placenta est au c\u0153ur de la r\u00e9gulation de la tol\u00e9rance au glucose maternelle pendant la grossesse, nous devons donc comprendre \u00e0 quel point l’apport FA affecte la fonction placentaire et, \u00e0 son tour, la r\u00e9sistance \u00e0 l’insuline et le risque de diab\u00e8te gestationnel\u00a0\u00bb, explique le Dr Jankovic-Marasoulos.<\/p>\n

Le professeur Claire Roberts de l’Universit\u00e9 de Flinders University NHMRC a d\u00e9clar\u00e9 que la compr\u00e9hension des dommages potentiels de l’apport en exc\u00e8s est d’une importance majeure en mati\u00e8re de sant\u00e9 publique.<\/p>\n

\u00ab\u00a0L’utilisation de la FA est recommand\u00e9e dans le monde entier, mais nous devons continuer \u00e0 \u00e9tudier les implications inattendues, ainsi que sur la fa\u00e7on d’identifier les femmes au d\u00e9but de la grossesse \u00e0 risque de diab\u00e8te gestationnel pour prot\u00e9ger le b\u00e9b\u00e9 contre les effets n\u00e9fastes de la glyc\u00e9mie maternelle \u00e9lev\u00e9e pour le meilleur d\u00e9but de la vie\u00a0\u00bb, a d\u00e9clar\u00e9 le professeur Roberts.<\/p>\n

Les chercheurs mettent l’accent sur l’importance d’un folate ad\u00e9quat pendant la grossesse, mais mettent en \u00e9vidence la n\u00e9cessit\u00e9 d’\u00e9tablir une limite sup\u00e9rieure s\u00fbre de l’apport en AF et d’am\u00e9liorer les directives sur la suppl\u00e9mentation en AF pendant la grossesse qui prot\u00e9gerait le f\u0153tus juste au d\u00e9but de la gestation contre les anomalies du tube neural mais prot\u00e9gerait \u00e9galement la m\u00e8re et le f\u0153tus contre les effets n\u00e9gatifs de la glyc\u00e9mie \u00e9lev\u00e9e.<\/p>\n

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Une consommation ad\u00e9quate de folates est recommand\u00e9e pour les femmes en pr\u00e9conception et en grossesse<\/p>\n","protected":false},"author":1,"featured_media":9444,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86],"tags":[288,102,159,6487,6655,6656,649,49,2071],"class_list":["post-9443","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-les-maladies","tag-chercheurs","tag-diabete","tag-entre","tag-excessif","tag-folate","tag-gestationnel","tag-identifient","tag-les","tag-lien","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50","resize-featured-image"],"yoast_head":"\nLes chercheurs identifient le lien entre le folate excessif et le diab\u00e8te gestationnel - RVH-Synergie.org<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rvh-synergie.org\/actualites\/les-chercheurs-identifient-le-lien-entre-le-folate-excessif-et-le-diabete-gestationnel\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Les chercheurs identifient le lien entre le folate excessif et le diab\u00e8te gestationnel - 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