{"id":9268,"date":"2025-09-10T08:18:07","date_gmt":"2025-09-10T06:18:07","guid":{"rendered":"https:\/\/rvh-synergie.org\/actualites\/emphyseme-sur-le-depistage-de-tomodensitometrie-a-faible-dose-predictif-de-la-mortalite-jusqua-25-ans\/"},"modified":"2025-09-10T08:18:08","modified_gmt":"2025-09-10T06:18:08","slug":"emphyseme-sur-le-depistage-de-tomodensitometrie-a-faible-dose-predictif-de-la-mortalite-jusqua-25-ans","status":"publish","type":"post","link":"https:\/\/rvh-synergie.org\/actualites\/emphyseme-sur-le-depistage-de-tomodensitometrie-a-faible-dose-predictif-de-la-mortalite-jusqua-25-ans\/","title":{"rendered":"Emphys\u00e8me sur le d\u00e9pistage de tomodensitom\u00e9trie \u00e0 faible dose pr\u00e9dictif de la mortalit\u00e9 jusqu’\u00e0 25 ans"},"content":{"rendered":"
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Pour les adultes ayant des ant\u00e9c\u00e9dents de tomodensitom\u00e9trie \u00e0 faible dose (LDCT) pour le d\u00e9pistage du cancer du poumon, l’emphys\u00e8me est pr\u00e9dictif de la mortalit\u00e9 jusqu’\u00e0 25 ans, selon une \u00e9tude publi\u00e9e en ligne le 9 septembre Radiologie<\/i>.<\/p>\n

Jessica Gonz\u00e1lez Gu\u00e9rrez, Ph.D., MPH, de l’h\u00f4pital universitaire d’Arnau de Vilanova et de Santa Maria \u00e0 Madrid, et des coll\u00e8gues ont men\u00e9 une \u00e9tude de cohorte prospective pour examiner si un seul score visuel d’emphys\u00e8me au LDCT est pr\u00e9dictif de la mortalit\u00e9 \u00e0 25 ans de toutes les causes, des maladies chroniques obstructuelles. Les adultes asymptomatiques \u00e2g\u00e9s de 40 \u00e0 85 ans avec des ant\u00e9c\u00e9dents de tabagisme ont subi un d\u00e9pistage de base du LDCT pour le cancer du poumon et ont \u00e9t\u00e9 suivis pour une m\u00e9diane de 23,3 ans.<\/p>\n

Les chercheurs ont constat\u00e9 que 2 637 (29,1%) des 9 047 participants avaient un emphys\u00e8me (l\u00e9ger, mod\u00e9r\u00e9 et s\u00e9v\u00e8re en 21,1%, 5,7% et 2,4%, respectivement). L’emphys\u00e8me \u00e9tait ind\u00e9pendamment pr\u00e9dictif de la mortalit\u00e9 toutes causes, de la mortalit\u00e9 de la MPOC et de la mortalit\u00e9 CVD (rapports de risque (intervalles de confiance \u00e0 95%), 1,29 (1,21 \u00e0 1,38; p <0,001), 3,29 (2,59 \u00e0 4,18; p <0,001) et 1,14 (1,01 \u00e0 1,29; p = 0,04), respectivement). Il y avait une relation dose-r\u00e9ponse observ\u00e9e entre la gravit\u00e9 de l'emphys\u00e8me et la mortalit\u00e9 toutes causes et la MPOC, qui n'a pas \u00e9t\u00e9 observ\u00e9e pour la mortalit\u00e9 des MCV.<\/p>\n

L’emphys\u00e8me est rest\u00e9 associ\u00e9 \u00e0 la mortalit\u00e9 de la MPOC (rapport de risque, 3,06; intervalle de confiance \u00e0 95%, 2,40 \u00e0 3,90; p <0,001), mais pas avec la mortalit\u00e9 CVD (rapport de risque, 1,04; intervalle de confiance \u00e0 95%, 0,91 \u00e0 1,18; p = 0,59), dans l'analyse du risque concurrente ajust\u00e9e.<\/p>\n

\u00ab\u00a0Cliniquement, ces r\u00e9sultats sugg\u00e8rent que l’emphys\u00e8me n’est pas simplement une conclusion de tomodensitom\u00e9trie accessoire, mais une entit\u00e9 de maladie distincte associ\u00e9e aux pires r\u00e9sultats et \u00e0 une mortalit\u00e9 accrue, non seulement \u00e0 partir du cancer du poumon, mais aussi \u00e0 partir des maladies respiratoires et cardiovasculaires\u00a0\u00bb, a d\u00e9clar\u00e9 Claudia I. Henschke, Ph.D.<\/p>\n

Plusieurs auteurs ont r\u00e9v\u00e9l\u00e9 des liens avec l’industrie de la technologie m\u00e9dicale.<\/p>\n

<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

Pour les adultes ayant des ant\u00e9c\u00e9dents de tomodensitom\u00e9trie \u00e0 faible dose (LDCT) pour le d\u00e9pistage<\/p>\n","protected":false},"author":1,"featured_media":9269,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86],"tags":[38,1002,534,6583,425,2741,820,2988,112,1532],"class_list":["post-9268","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-les-maladies","tag-ans","tag-depistage","tag-dose","tag-emphyseme","tag-faible","tag-jusqua","tag-mortalite","tag-predictif","tag-sur","tag-tomodensitometrie","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50","resize-featured-image"],"yoast_head":"\nEmphys\u00e8me sur le d\u00e9pistage de tomodensitom\u00e9trie \u00e0 faible dose pr\u00e9dictif de la mortalit\u00e9 jusqu'\u00e0 25 ans - RVH-Synergie.org<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rvh-synergie.org\/actualites\/emphyseme-sur-le-depistage-de-tomodensitometrie-a-faible-dose-predictif-de-la-mortalite-jusqua-25-ans\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Emphys\u00e8me sur le d\u00e9pistage de tomodensitom\u00e9trie \u00e0 faible dose pr\u00e9dictif de la mortalit\u00e9 jusqu'\u00e0 25 ans - 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