{"id":909,"date":"2024-09-28T01:04:00","date_gmt":"2024-09-27T23:04:00","guid":{"rendered":"https:\/\/rvh-synergie.org\/actualites\/deux-etudes-revelent-que-le-virus-sars-cov-2-devient-resistant-aux-medicaments-antiviraux-utilises-pour-traiter-les-patients\/"},"modified":"2024-09-28T01:04:08","modified_gmt":"2024-09-27T23:04:08","slug":"deux-etudes-revelent-que-le-virus-sars-cov-2-devient-resistant-aux-medicaments-antiviraux-utilises-pour-traiter-les-patients","status":"publish","type":"post","link":"https:\/\/rvh-synergie.org\/actualites\/deux-etudes-revelent-que-le-virus-sars-cov-2-devient-resistant-aux-medicaments-antiviraux-utilises-pour-traiter-les-patients\/","title":{"rendered":"Deux \u00e9tudes r\u00e9v\u00e8lent que le virus SARS-CoV-2 devient r\u00e9sistant aux m\u00e9dicaments antiviraux utilis\u00e9s pour traiter les patients"},"content":{"rendered":"
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Deux \u00e9tudes ont r\u00e9v\u00e9l\u00e9 que le virus responsable du COVID-19 devient r\u00e9sistant \u00e0 deux m\u00e9dicaments utilis\u00e9s pour traiter les patients infect\u00e9s.<\/p>\n

Dans la premi\u00e8re \u00e9tude, une \u00e9quipe combin\u00e9e de l’Universit\u00e9 Cornell et des National Institutes of Health a \u00e9tudi\u00e9 les r\u00e9sultats du traitement pour les patients dont le syst\u00e8me immunitaire est affaibli et qui ont re\u00e7u le m\u00e9dicament remdesivir. Ils ont publi\u00e9 leurs r\u00e9sultats dans la revue Communications naturelles<\/i>.<\/p>\n

Dans la deuxi\u00e8me \u00e9tude, une \u00e9quipe de chercheurs de l’Universit\u00e9 de Pittsburgh, du Brigham and Women’s Hospital, de l’Universit\u00e9 de Stanford et de l’Universit\u00e9 de Harvard a \u00e9tudi\u00e9 les r\u00e9sultats pour les patients atteints de COVID-19 ayant re\u00e7u des m\u00e9dicaments antiviraux au cours des ann\u00e9es 2021 \u00e0 2023. Ils ont publi\u00e9 leurs r\u00e9sultats dans la revue R\u00e9seau JAMA ouvert<\/i>.<\/p>\n

Zhuo Zhou et Peng Hong, respectivement de l’Acad\u00e9mie chinoise des sciences m\u00e9dicales, du Peking Union Medical College et du VA New York Harbor Healthcare System, ont publi\u00e9 un commentaire dans le m\u00eame R\u00e9seau JAMA ouvert<\/i> num\u00e9ro d\u00e9crivant le travail de la deuxi\u00e8me \u00e9quipe.<\/p>\n

Dans les ann\u00e9es qui ont suivi le pic de la pand\u00e9mie de COVID-19, les chercheurs en m\u00e9decine ont continu\u00e9 \u00e0 \u00e9tudier le SRAS-CoV-2, ainsi que de nouvelles options vaccinales. Ils ont \u00e9galement travaill\u00e9 au d\u00e9veloppement de nouveaux traitements pour les personnes infect\u00e9es par le virus mais qui n\u2019ont pas \u00e9t\u00e9 immunis\u00e9es ou dont le syst\u00e8me immunitaire est affaibli.<\/p>\n

Dans le cadre de cet effort, deux de ces th\u00e9rapies, appel\u00e9es remdesivir et nirmatrelvir, sont devenues les m\u00e9dicaments de r\u00e9f\u00e9rence pour les patients dont le syst\u00e8me immunitaire n’est pas capable de combattre le virus. Mais comme ils sont antiviraux, ils courent le risque de devenir obsol\u00e8tes \u00e0 mesure que le virus mute.<\/p>\n

Dans la premi\u00e8re \u00e9tude, les chercheurs ont s\u00e9quenc\u00e9 l\u2019ADN du virus infectant 15 patients atteints de COVID et ont d\u00e9couvert que le virus avait d\u00e9velopp\u00e9 une sensibilit\u00e9 r\u00e9duite au remdesivir et au nirmatrelvir. Ils ont \u00e9galement d\u00e9couvert que les virus mut\u00e9s pourraient infecter d\u2019autres personnes \u00e0 proximit\u00e9. Une note positive : les chercheurs ont d\u00e9couvert que l\u2019administration des deux antiviraux aux patients \u00e9liminait le virus.<\/p>\n

Dans la deuxi\u00e8me \u00e9tude, l\u2019\u00e9quipe de recherche a \u00e9tudi\u00e9 le traitement de 156 patients atteints du COVID-19 sur deux ans. Dans le cadre de cet effort, les chercheurs ont divis\u00e9 les patients en deux groupes : ceux qui avaient re\u00e7u les m\u00e9dicaments antiviraux et ceux qui ne l\u2019avaient pas re\u00e7u. Les virus pr\u00e9sentant des mutations r\u00e9sistantes aux antiviraux \u00e9taient plus susceptibles d\u2019\u00eatre d\u00e9tect\u00e9s chez les patients ayant re\u00e7u des m\u00e9dicaments antiviraux. L\u2019effet \u00e9tait plus \u00e9vident chez les personnes immunod\u00e9prim\u00e9es et chez celles qui avaient re\u00e7u du nirmatrelvir.<\/p>\n

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Deux \u00e9tudes ont r\u00e9v\u00e9l\u00e9 que le virus responsable du COVID-19 devient r\u00e9sistant \u00e0 deux m\u00e9dicaments<\/p>\n","protected":false},"author":1,"featured_media":910,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86],"tags":[1163,171,273,1161,1041,49,87,616,8,1162,149,1160,1165,1164,630],"class_list":["post-909","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-les-maladies","tag-antiviraux","tag-aux","tag-deux","tag-devient","tag-etudes","tag-les","tag-medicaments","tag-patients","tag-pour","tag-resistant","tag-revelent","tag-sarscov2","tag-traiter","tag-utilises","tag-virus","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50","resize-featured-image"],"yoast_head":"\nDeux \u00e9tudes r\u00e9v\u00e8lent que le virus SARS-CoV-2 devient r\u00e9sistant aux m\u00e9dicaments antiviraux utilis\u00e9s pour traiter les patients - 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