{"id":6758,"date":"2025-05-24T14:56:51","date_gmt":"2025-05-24T12:56:51","guid":{"rendered":"https:\/\/rvh-synergie.org\/actualites\/la-transplantation-renale-preemptive-preventive-ne-reduit-pas-le-risque-de-deces-trouve-la-recherche\/"},"modified":"2025-05-24T14:56:55","modified_gmt":"2025-05-24T12:56:55","slug":"la-transplantation-renale-preemptive-preventive-ne-reduit-pas-le-risque-de-deces-trouve-la-recherche","status":"publish","type":"post","link":"https:\/\/rvh-synergie.org\/actualites\/la-transplantation-renale-preemptive-preventive-ne-reduit-pas-le-risque-de-deces-trouve-la-recherche\/","title":{"rendered":"La transplantation r\u00e9nale pr\u00e9emptive pr\u00e9ventive ne r\u00e9duit pas le risque de d\u00e9c\u00e8s, trouve la recherche"},"content":{"rendered":"
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De nouvelles recherches r\u00e9v\u00e8lent que les premi\u00e8res greffes de rein pr\u00e9emptive ne r\u00e9duisent pas le risque de d\u00e9c\u00e8s, selon une \u00e9tude de la Yale School of Medicine (YSM) publi\u00e9e dans Proc\u00e9dure de transplantation<\/i>.<\/p>\n

La maladie r\u00e9nale en phase terminale (ESKD), \u00e9galement connue sous le nom d’insuffisance r\u00e9nale ou r\u00e9nale, peut se produire en raison du diab\u00e8te et de l’hypertension art\u00e9rielle, entre autres raisons. Un patient souffrant d’insuffisance r\u00e9nale a besoin d’une greffe lorsqu’il commence la dialyse, ou peut-\u00eatre auparavant. \u00c9tant donn\u00e9 que la dialyse met le stress sur le corps et affaiblit le syst\u00e8me immunitaire, il est commun\u00e9ment cru que les personnes atteintes d’ESKD auraient de meilleurs r\u00e9sultats si elles re\u00e7oivent une greffe de rein de mani\u00e8re pr\u00e9ventive – avant de recevoir la dialyse.<\/p>\n

L’\u00e9tude, dirig\u00e9e par Abhishek Kumar, MBBS, professeur agr\u00e9g\u00e9 de m\u00e9decine (n\u00e9phrologie) \u00e0 YSM et directeur m\u00e9dical du programme de donneurs de reins vivants \u00e0 Yale, a examin\u00e9 les dossiers au cours de deux d\u00e9cennies pour \u00e9valuer l’\u00e9tat actuel de transplantations r\u00e9nales pr\u00e9ventives aux \u00c9tats-Unis, en se concentrant sur les avantages de la mortalit\u00e9. Kumar et ses coll\u00e8gues \u00e9taient int\u00e9ress\u00e9s \u00e0 d\u00e9couvrir s’il y avait un avantage \u00e0 effectuer une greffe plus t\u00f4t par rapport \u00e0 plus tard des donateurs d\u00e9c\u00e9d\u00e9s et vivants.<\/p>\n

\u00ab\u00a0Si vous recevez un organe de la liste des donateurs d\u00e9c\u00e9d\u00e9s, vous n’avez pas de contr\u00f4le sur le moment o\u00f9 vous obtiendrez l’orgue\u00a0\u00bb, explique Kumar. \u00ab\u00a0D’un autre c\u00f4t\u00e9, s’il y a un donneur vivant et que vous avez plus de contr\u00f4le sur le timing, la question est, quand est-il le plus avantageux d’obtenir la greffe?\u00a0\u00bb<\/p>\n

Les r\u00e9sultats ne pr\u00e9sentent aucune diff\u00e9rence dans les r\u00e9sultats de la mortalit\u00e9 pour ceux qui ont re\u00e7u une greffe r\u00e9nale plus t\u00f4t lorsqu’ils avaient un taux de filtration glom\u00e9rulaire estim\u00e9 plus \u00e9lev\u00e9 (EGFR), une mesure de la fonction r\u00e9nale, ou plus tard que l’EGFR a aggrav\u00e9. Par cons\u00e9quent, dit Kumar, les patients devraient attendre s’ils ont le choix.<\/p>\n

\u00ab\u00a0Tout est question de timing\u00a0\u00bb, explique Kumar. \u00ab\u00a0Notre \u00e9tude montre que l’attente d’avoir vraiment besoin d’une greffe, c’est quand vous devriez en avoir un. Sinon, vous perdez ce temps sur votre propre rein.<\/p>\n

\u00ab\u00a0Parfois, je dis aux patients le meilleur moment pour obtenir une greffe est le jour o\u00f9 vous avez besoin de dialyse\u00a0\u00bb, ajoute-t-il.<\/p>\n

L’exposition \u00e0 la dialyse jusqu’\u00e0 six mois n’a pas d’impact n\u00e9gatif sur les r\u00e9sultats \u00e0 long terme si une transplantation est effectu\u00e9e dans cette p\u00e9riode, dit Kumar.<\/p>\n

Cependant, le temps optimal pour la dialyse et la transplantation d\u00e9pend de l’individu et est difficile \u00e0 pr\u00e9voir, explique Kumar, qui note que la transition des soins de la maladie r\u00e9nale chronique \u00e0 la dialyse est co\u00fbteuse et \u00e0 forte intensit\u00e9 de ressources.<\/p>\n

\u00ab\u00a0Nous devons toujours \u00e9viter la dialyse si nous le pouvons, mais effectuer une greffe t\u00f4t n’est pas la solution.\u00a0\u00bb<\/p>\n

<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

De nouvelles recherches r\u00e9v\u00e8lent que les premi\u00e8res greffes de rein pr\u00e9emptive ne r\u00e9duisent pas le<\/p>\n","protected":false},"author":1,"featured_media":6759,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86],"tags":[301,359,5433,5434,499,658,249,40,1976,1456],"class_list":["post-6758","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-les-maladies","tag-deces","tag-pas","tag-preemptive","tag-preventive","tag-recherche","tag-reduit","tag-renale","tag-risque","tag-transplantation","tag-trouve","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50","resize-featured-image"],"yoast_head":"\nLa transplantation r\u00e9nale pr\u00e9emptive pr\u00e9ventive ne r\u00e9duit pas le risque de d\u00e9c\u00e8s, trouve la recherche - RVH-Synergie.org<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rvh-synergie.org\/actualites\/la-transplantation-renale-preemptive-preventive-ne-reduit-pas-le-risque-de-deces-trouve-la-recherche\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La transplantation r\u00e9nale pr\u00e9emptive pr\u00e9ventive ne r\u00e9duit pas le risque de d\u00e9c\u00e8s, trouve la recherche - 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