{"id":6330,"date":"2025-05-07T18:58:09","date_gmt":"2025-05-07T16:58:09","guid":{"rendered":"https:\/\/rvh-synergie.org\/actualites\/les-parasites-des-schistosomes-hybrides-menent-a-des-appels-a-de-nouvelles-methodes-de-diagnostic\/"},"modified":"2025-05-07T18:58:10","modified_gmt":"2025-05-07T16:58:10","slug":"les-parasites-des-schistosomes-hybrides-menent-a-des-appels-a-de-nouvelles-methodes-de-diagnostic","status":"publish","type":"post","link":"https:\/\/rvh-synergie.org\/actualites\/les-parasites-des-schistosomes-hybrides-menent-a-des-appels-a-de-nouvelles-methodes-de-diagnostic\/","title":{"rendered":"Les parasites des schistosomes hybrides m\u00e8nent \u00e0 des appels \u00e0 de nouvelles m\u00e9thodes de diagnostic"},"content":{"rendered":"
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Des chercheurs de la Liverpool School of Tropical Medicine (LSTM) et du Malawi ont r\u00e9v\u00e9l\u00e9 de nouvelles preuves d’esp\u00e8ces de schistosomes hybrides zoonotiques infectant les humains, ce qui soul\u00e8ve des pr\u00e9occupations concernant le diagnostic et la pr\u00e9valence de la schistosomiase.<\/p>\n

L’\u00e9tude, publi\u00e9e dans les CDC Maladies infectieuses \u00e9mergentes<\/i>d\u00e9crit de nouveaux cas de schistosomiase intestinale et urog\u00e9nitale mixte chez les patients du district de Mangochi, Malawi. Bien que les individus se soient test\u00e9s positifs pour la schistosomiase urog\u00e9nitale humaine en utilisant des tests de diagnostic d’urine standard, leurs \u00e9chantillons f\u00e9caux ont \u00e9galement r\u00e9v\u00e9l\u00e9 de nombreux \u0153ufs parasitaires hybrides.<\/p>\n

Les \u0153ufs provenaient de la prog\u00e9niture de Schistosoma Haematobium et S. Mattheei, un parasite de l’\u00e9levage, ainsi que des preuves que S. Mattheei s’\u00e9tait m\u00e9lang\u00e9e avec S. mansoni, l’esp\u00e8ce normalement associ\u00e9e \u00e0 une infection intestinale humaine.<\/p>\n

Ces r\u00e9sultats offrent de nouveaux informations sur la complexit\u00e9 croissante de la transmission de la schistosomiase o\u00f9 les changements environnementaux et les habitats d’escargot qui se chevauchent ont cr\u00e9\u00e9 des conditions pour l’hybridation inter-esp\u00e8ces. Ils remettent \u00e9galement en question les r\u00e9gimes de diagnostic actuels conseill\u00e9es par l’Organisation mondiale de la sant\u00e9 (OMS) qui s’appuient sur des \u00e9chantillons d’urine. Les \u0153ufs d’esp\u00e8ces hybrides zoonotiques ont \u00e9t\u00e9 principalement trouv\u00e9s dans des \u00e9chantillons f\u00e9caux, ce qui sugg\u00e8re que des infections intestinales pouvaient \u00eatre manqu\u00e9es.<\/p>\n

Angus O’Ferrall, doctorant et auteur principal de l’\u00e9tude, a d\u00e9clar\u00e9: \u00ab\u00a0Qui recommande d’utiliser des tremblements d’urine pour cartographier les maladies intestinales, mais la d\u00e9couverte d’\u0153ufs zoonotiques et hybrides dans les voies intestinales humaines sugg\u00e8re que l’approche pourrait \u00eatre trop \u00e9troite, et nous pouvons manquer des infections hybrides intestinales.\u00a0\u00bb<\/p>\n

\u00ab\u00a0Nos r\u00e9sultats soulignent la n\u00e9cessit\u00e9 de strat\u00e9gies d’\u00e9chantillonnage plus compl\u00e8tes et l’expansion des recommandations de test dans les domaines o\u00f9 les humains et l’\u00e9levage partagent l’eau.\u00a0\u00bb<\/p>\n

Bien que l’hybridation entre les esp\u00e8ces de schistosomes ait \u00e9t\u00e9 signal\u00e9e pr\u00e9c\u00e9demment, il s’agit de la premi\u00e8re preuve d’hybrides du groupe S. haematobium contribuant \u00e0 l’infection intestinale chez l’homme.<\/p>\n

L’\u00e9tude appelle \u00e0 une surveillance \u00e9largie dans les zones co-end\u00e9miques, y compris l’examen de routine d’\u00e9chantillons f\u00e9caux aux c\u00f4t\u00e9s de l’urine, et le d\u00e9ploiement d’outils mol\u00e9culaires capables d’identifier les esp\u00e8ces hybrides. Ces \u00e9tapes sont essentielles pour assurer un diagnostic pr\u00e9cis et un traitement efficace.<\/p>\n

Le professeur Russell Stothard, chef du projet HUGS (hybridation dans la schistosomiase urog\u00e9nitale) au LSTM, a ajout\u00e9: \u00ab\u00a0Alors que nous approfondissons notre compr\u00e9hension de la g\u00e9nomique des schistosomes, nous devons \u00e9galement adapter nos outils de terrain et les strat\u00e9gies de sant\u00e9 publique en cons\u00e9quence. En particulier les parasites hybrides ne sont pas seulement une curiosit\u00e9 scientifique, ils ont de r\u00e9els implications pour les programmes de contr\u00f4le, en particulier dans les parasites avec des contacts humains.<\/p>\n

Les auteurs de l’\u00e9tude soulignent la n\u00e9cessit\u00e9 de recherches suppl\u00e9mentaires pour d\u00e9terminer la pr\u00e9valence des schistosomes zoonotiques et hybrides au Malawi et au-del\u00e0, et pour explorer leur impact sur la charge de la maladie et les efforts de contr\u00f4le.<\/p>\n

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Des chercheurs de la Liverpool School of Tropical Medicine (LSTM) et du Malawi ont r\u00e9v\u00e9l\u00e9<\/p>\n","protected":false},"author":1,"featured_media":6331,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86],"tags":[2173,16,1391,5210,49,2708,553,1189,3916,5209],"class_list":["post-6330","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-les-maladies","tag-appels","tag-des","tag-diagnostic","tag-hybrides","tag-les","tag-menent","tag-methodes","tag-nouvelles","tag-parasites","tag-schistosomes","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50","resize-featured-image"],"yoast_head":"\nLes parasites des schistosomes hybrides m\u00e8nent \u00e0 des appels \u00e0 de nouvelles m\u00e9thodes de diagnostic - RVH-Synergie.org<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rvh-synergie.org\/actualites\/les-parasites-des-schistosomes-hybrides-menent-a-des-appels-a-de-nouvelles-methodes-de-diagnostic\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Les parasites des schistosomes hybrides m\u00e8nent \u00e0 des appels \u00e0 de nouvelles m\u00e9thodes de diagnostic - 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