{"id":4369,"date":"2025-02-17T09:58:54","date_gmt":"2025-02-17T08:58:54","guid":{"rendered":"https:\/\/rvh-synergie.org\/actualites\/comment-sars-cov-2-a-evolue-a-travers-la-pandemie\/"},"modified":"2025-02-17T09:58:56","modified_gmt":"2025-02-17T08:58:56","slug":"comment-sars-cov-2-a-evolue-a-travers-la-pandemie","status":"publish","type":"post","link":"https:\/\/rvh-synergie.org\/actualites\/comment-sars-cov-2-a-evolue-a-travers-la-pandemie\/","title":{"rendered":"Comment SARS-COV-2 a \u00e9volu\u00e9 \u00e0 travers la pand\u00e9mie"},"content":{"rendered":"
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Une nouvelle \u00e9tude de chercheurs de Weill Cornell Medicine-Qatar (WCM-Q) r\u00e9v\u00e8le comment le virus SARS-COV-2 a \u00e9volu\u00e9 de la priorit\u00e9 initiale de la transmissibilit\u00e9 accrue pour am\u00e9liorer l’\u00e9vasion immunitaire apr\u00e8s que la variante omicron ait \u00e9merg\u00e9.<\/p>\n

Au cours de la pand\u00e9mie, le virus a subi des mutations g\u00e9n\u00e9tiques rapides qui ont conduit \u00e0 plusieurs variantes avec des capacit\u00e9s diff\u00e9rentes pour se propager entre les individus, provoquer des infections graves et \u00e9chapper au syst\u00e8me immunitaire.<\/p>\n

L’\u00e9tude, publi\u00e9e dans Nature<\/i>a \u00e9t\u00e9 men\u00e9 par une collaboration bas\u00e9e au Qatar de six institutions et pr\u00e9sente des analyses \u00e9pid\u00e9miologiques au niveau de la population sur plus de 1,5 million de personnes, couvrant la p\u00e9riode de quatre ans \u00e0 partir du d\u00e9but de la pand\u00e9mie.<\/p>\n

L’\u00e9tude a r\u00e9v\u00e9l\u00e9 qu’avant que la variante omicron n’ait \u00e9merg\u00e9 fin 2021, l’immunit\u00e9 naturelle tir\u00e9e d’une infection pr\u00e9c\u00e9dente a fourni une protection soutenue et robuste contre la r\u00e9infection avec environ 80% d’efficacit\u00e9. Cependant, apr\u00e8s que l’omicron est devenu la souche dominante, la protection immunitaire n’\u00e9tait forte que chez les individus r\u00e9cemment infect\u00e9s et a rapidement refus\u00e9 des niveaux n\u00e9gligeables dans un an. Ces tendances \u00e9taient coh\u00e9rentes, que la r\u00e9infection ait \u00e9t\u00e9 consid\u00e9r\u00e9e comme toute infection ou limit\u00e9e aux cas symptomatiques.<\/p>\n

\u00ab\u00a0Cette \u00e9volution continue et cette \u00e9vasion immunitaire rendent difficile la r\u00e9alisation de l’immunit\u00e9 \u00e0 long terme de la population contre le virus\u00a0\u00bb, a d\u00e9clar\u00e9 Hiam Chemitelly, premier auteur de l’\u00e9tude et professeur adjoint de recherche en sciences de la sant\u00e9 de la population chez WCM-Q. \u00ab\u00a0L’immunit\u00e9 de courte dur\u00e9e conduit \u00e0 des vagues r\u00e9p\u00e9t\u00e9es d’infection, des mod\u00e8les refl\u00e9tants observ\u00e9s avec des coronavirus froids et de la grippe.\u00a0\u00bb<\/p>\n

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Les r\u00e9sultats indiquent que l’\u00e9mergence d’Omicron a marqu\u00e9 un tournant dans la pand\u00e9mie. Avant Omicron – lorsque la majeure partie de la population n’est rest\u00e9e pas infect\u00e9e en raison d’interventions g\u00e9n\u00e9ralis\u00e9es de sant\u00e9 publique – le virus a \u00e9volu\u00e9 par des mutations g\u00e9n\u00e9tiques qui ont augment\u00e9 sa capacit\u00e9 \u00e0 se propager d’une personne en personne. Dans cette phase, des variantes plus transmissibles, telles que Alpha et Delta, ont \u00e9merg\u00e9.<\/p>\n

En revanche, pendant l’\u00e8re omicron, les infections ant\u00e9rieures et les vaccinations ont g\u00e9n\u00e9r\u00e9 une immunit\u00e9 g\u00e9n\u00e9ralis\u00e9e qui a fait pression sur le virus pour \u00e9voluer des m\u00e9canismes pour \u00e9chapper aux d\u00e9fenses immunitaires d’une personne, entra\u00eenant un d\u00e9clin rapide de l’immunit\u00e9 naturelle contre la r\u00e9infection. Ce changement a donn\u00e9 lieu \u00e0 des subvariants tr\u00e8s g\u00e9n\u00e9tiquement diverses d’Omicron, tels que XBB et JN.1.<\/p>\n

\u00ab\u00a0Ce virus est l\u00e0 pour rester et continuera de nous r\u00e9infecter\u00a0\u00bb, a d\u00e9clar\u00e9 Chemitelly. \u00ab\u00a0Les mises \u00e0 jour r\u00e9guli\u00e8res du vaccin sont essentielles pour renouveler l’immunit\u00e9 et prot\u00e9ger les populations vuln\u00e9rables, en particulier les personnes \u00e2g\u00e9es et les personnes souffrant de probl\u00e8mes de sant\u00e9 sous-jacents.\u00a0\u00bb<\/p>\n

\u00ab\u00a0Le virus a montr\u00e9 une adaptabilit\u00e9 remarquable, lui permettant de persister dans les populations humaines et de provoquer des r\u00e9infections r\u00e9p\u00e9t\u00e9es\u00a0\u00bb, a d\u00e9clar\u00e9 Laith Abu-Raddad, auteur principal de l’\u00e9tude et professeur de sciences de la sant\u00e9 de la population chez WCM-Q. \u00ab\u00a0Heureusement, ceux-ci sont presque toujours l\u00e9gers ou asymptomatiques. Bien que le virus reste \u00e0 faire partie de notre vie, il ne constituera plus la m\u00eame menace grave que lors de sa premi\u00e8re \u00e9mergence.\u00a0\u00bb<\/p>\n

<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

Une nouvelle \u00e9tude de chercheurs de Weill Cornell Medicine-Qatar (WCM-Q) r\u00e9v\u00e8le comment le virus SARS-COV-2<\/p>\n","protected":false},"author":1,"featured_media":4370,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86],"tags":[182,4071,454,1160,1350],"class_list":["post-4369","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-les-maladies","tag-comment","tag-evolue","tag-pandemie","tag-sarscov2","tag-travers","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50","resize-featured-image"],"yoast_head":"\nComment SARS-COV-2 a \u00e9volu\u00e9 \u00e0 travers la pand\u00e9mie - RVH-Synergie.org<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rvh-synergie.org\/actualites\/comment-sars-cov-2-a-evolue-a-travers-la-pandemie\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Comment SARS-COV-2 a \u00e9volu\u00e9 \u00e0 travers la pand\u00e9mie - 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