{"id":3799,"date":"2025-01-25T05:55:53","date_gmt":"2025-01-25T04:55:53","guid":{"rendered":"https:\/\/rvh-synergie.org\/actualites\/une-etude-revele-que-des-tests-evolutifs-identifient-les-personnes-a-risque\/"},"modified":"2025-01-25T05:55:57","modified_gmt":"2025-01-25T04:55:57","slug":"une-etude-revele-que-des-tests-evolutifs-identifient-les-personnes-a-risque","status":"publish","type":"post","link":"https:\/\/rvh-synergie.org\/actualites\/une-etude-revele-que-des-tests-evolutifs-identifient-les-personnes-a-risque\/","title":{"rendered":"Une \u00e9tude r\u00e9v\u00e8le que des tests \u00e9volutifs identifient les personnes \u00e0 risque"},"content":{"rendered":"
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De nouvelles recherches soulignent la n\u00e9cessit\u00e9 d\u2019une protection continue contre le COVID-19 pour les personnes dont le syst\u00e8me immunitaire est affaibli, avec des tests \u00e9volutifs aidant \u00e0 identifier les personnes les plus \u00e0 risque pour permettre des strat\u00e9gies adapt\u00e9es.<\/p>\n

La recherche, publi\u00e9e dans La Lancette<\/i>et impliquant des experts de l’Universit\u00e9 de Nottingham et du Nottingham University Hospitals NHS Trust, r\u00e9v\u00e8le comment un simple test sanguin peut pr\u00e9dire la gravit\u00e9 de l’infection au COVID-19, ouvrant la voie \u00e0 des approches personnalis\u00e9es de vaccination et \u00e0 une meilleure protection pour les personnes les plus \u00e0 risque.<\/p>\n

L\u2019\u00e9tude MELODY (Mass Evaluation of Lateral Flow Immunoassays for the Detection of SARS-CoV-2 Antibody in Immunosuppressed People) a explor\u00e9 dans quelle mesure les individus \u00e0 risque d\u00e9veloppent des anticorps apr\u00e8s au moins trois vaccinations contre le COVID-19. Les anticorps sont essentiels pour que l\u2019organisme combatte l\u2019infection, mais les patients prenant des m\u00e9dicaments immunosuppresseurs peuvent r\u00e9pondre moins efficacement aux vaccins.<\/p>\n

L’\u00e9tude MELODY est la plus grande du genre, impliquant plus de 28 000 participants. Les personnes immunod\u00e9prim\u00e9es constituent un groupe souvent n\u00e9glig\u00e9 dans la recherche sur le COVID-19.<\/p>\n

L’\u00e9tude a \u00e9t\u00e9 dirig\u00e9e par des experts de l’Imperial College de Londres et l’auteur principal principal \u00e9tait le Dr Fiona Pearce de l’unit\u00e9 de dur\u00e9e de vie et de sant\u00e9 de la population de la facult\u00e9 de m\u00e9decine de l’universit\u00e9 de Nottingham.<\/p>\n

\u00ab L’\u00e9tude MELODY illustre la puissance et la valeur de l’enregistrement national des maladies, permettant l’inclusion de groupes habituellement exclus de la recherche. C’est une fiert\u00e9 que MELODY ait r\u00e9ussi \u00e0 recruter trois groupes immunod\u00e9prim\u00e9s, y compris des personnes atteintes de maladies rhumatismales auto-immunes rares \u00bb, d\u00e9clare le Dr Pearce.<\/p>\n

\u00a0\u00bb L’inclusion de ce groupe de plus de 6\u00a0000 personnes atteintes de maladies rhumatismales auto-immunes rares a \u00e9t\u00e9 rendue possible gr\u00e2ce au travail r\u00e9volutionnaire du groupe RECORDER de l’Universit\u00e9 de Nottingham, en partenariat avec le National Disease Registration Service du NHS England. Jusqu’\u00e0 pr\u00e9sent, ils avaient \u00e9t\u00e9 non identifiable et exclu de la recherche nationale.<\/p>\n

Entre d\u00e9cembre 2021 et juin 2022, les participants ont utilis\u00e9 des kits de tests \u00e0 domicile comprenant un simple test sanguin par piq\u00fbre au doigt pour mesurer les niveaux d’anticorps de longue dur\u00e9e, en employant des m\u00e9thodes mises au point dans le cadre de l’\u00e9tude REACT, l’une des \u00e9tudes de surveillance des coronavirus les plus vastes et les plus compl\u00e8tes au monde. Contrairement aux tests COVID-19 standard, ces tests v\u00e9rifient la protection immunitaire.<\/p>\n

L\u2019\u00e9tude a r\u00e9v\u00e9l\u00e9 que 82 % des patients ont d\u00e9velopp\u00e9 des anticorps apr\u00e8s la vaccination. Ceux qui avaient des anticorps d\u00e9tectables \u00e9taient moins susceptibles de contracter le virus ou de n\u00e9cessiter des soins hospitaliers en cas d’infection.<\/p>\n

Le Dr Willicombe, lecteur clinique \u00e0 l’Imperial College de Londres et n\u00e9phrologue consultant honoraire \u00e0 l’Imperial College Healthcare NHS Trust, a d\u00e9clar\u00e9 : \u00ab Bien qu’il soit vraiment rassurant de voir que la plupart des patients de ce groupe ont bien r\u00e9pondu \u00e0 la vaccination, nous savons que cette approche peut \u00eatre moins efficace. chez certains patients trait\u00e9s avec certains m\u00e9dicaments immunosuppresseurs, et une attention particuli\u00e8re \u00e0 toute strat\u00e9gie de protection est n\u00e9cessaire.<\/p>\n

\u00ab MELODY a montr\u00e9 qu’il est possible d’\u00e9valuer individuellement la r\u00e9ponse vaccinale et le risque de cons\u00e9quences graves suite \u00e0 une infection au COVID-19 dans ce groupe. Ces informations ont le potentiel de soutenir des approches personnalis\u00e9es de pr\u00e9vention du COVID-19, telles que des calendriers ou des traitements de vaccination individualis\u00e9s. aider les patients \u00e0 risque \u00e0 b\u00e9n\u00e9ficier plus \u00e9quitablement des mesures de sant\u00e9 publique disponibles.<\/p>\n

\u00ab Cela montre pourquoi il est important que toutes les personnes immunod\u00e9prim\u00e9es maximisent leur protection en restant \u00e0 jour avec tous leurs vaccins \u00e9ligibles, y compris contre la COVID-19 et la grippe \u00bb, explique le Dr Peter Lanyon.<\/p>\n

Les r\u00e9sultats soulignent l\u2019importance d\u2019adapter les mesures de sant\u00e9 pour r\u00e9pondre aux besoins des patients vuln\u00e9rables, garantissant que chacun b\u00e9n\u00e9ficie des progr\u00e8s de la m\u00e9decine et de la sant\u00e9 publique.<\/p>\n

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De nouvelles recherches soulignent la n\u00e9cessit\u00e9 d\u2019une protection continue contre le COVID-19 pour les personnes<\/p>\n","protected":false},"author":1,"featured_media":3800,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86],"tags":[16,48,3697,649,49,100,157,40,72,47],"class_list":["post-3799","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-les-maladies","tag-des","tag-etude","tag-evolutifs","tag-identifient","tag-les","tag-personnes","tag-revele","tag-risque","tag-tests","tag-une","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50","resize-featured-image"],"yoast_head":"\nUne \u00e9tude r\u00e9v\u00e8le que des tests \u00e9volutifs identifient les personnes \u00e0 risque - RVH-Synergie.org<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rvh-synergie.org\/actualites\/une-etude-revele-que-des-tests-evolutifs-identifient-les-personnes-a-risque\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Une \u00e9tude r\u00e9v\u00e8le que des tests \u00e9volutifs identifient les personnes \u00e0 risque - 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