{"id":20559,"date":"2026-10-21T06:11:10","date_gmt":"2026-10-21T04:11:10","guid":{"rendered":"https:\/\/rvh-synergie.org\/actualites\/le-gene-crazy-one-rend-resistant-aux-champignons-hospitaliers-mortels\/"},"modified":"2026-10-21T06:11:11","modified_gmt":"2026-10-21T04:11:11","slug":"le-gene-crazy-one-rend-resistant-aux-champignons-hospitaliers-mortels","status":"publish","type":"post","link":"https:\/\/rvh-synergie.org\/actualites\/le-gene-crazy-one-rend-resistant-aux-champignons-hospitaliers-mortels\/","title":{"rendered":"Le g\u00e8ne \u00ab Crazy One \u00bb rend r\u00e9sistant aux champignons hospitaliers mortels"},"content":{"rendered":"<p><!--$--><br \/>\n<!--\/--><br \/>\n<!--$--><\/p>\n<div data-hk=\"0000a124212000a23100\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>Un m\u00e9canisme sp\u00e9cial aide le champignon hospitalier mortel Candidozyma auris \u00e0 \u00e9chapper au traitement. Un g\u00e8ne appel\u00e9 \u00ab Crazy-one \u00bb est impliqu\u00e9, rapporte une \u00e9quipe de recherche dans la revue \u00ab Nature Communications \u00bb.<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a23110\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>Le champignon produit des copies suppl\u00e9mentaires de son g\u00e9nome entier sous la pression des m\u00e9dicaments, augmentant ainsi la probabilit\u00e9 que certains changements \u2013 comme ceux du g\u00e8ne \u00ab Crazy-one \u00bb (CRZ1) \u2013 conduisent \u00e0 une r\u00e9sistance.<\/p>\n<\/div>\n<aside data-hk=\"0000a124212000a2312004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-mobile Ad-Slot-hor Ad-Slot-FC\">\n<div class=\"Ad-Slot-FC-Container \" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\">\n<div class=\"Ad-Slot-FC-Window\">\n<div id=\"ad-slot-mobile-hor-2\" data-orientation=\"hor\" data-index=\"2\" data-slot=\"ad-slot\" data-device=\"mobile\"><\/div>\n<\/div>\n<\/div>\n<\/aside>\n<div data-hk=\"0000a124212000a23130\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<h2>Le champignon hospitalier est une \u00ab menace mortelle \u00bb pour les patients en soins intensifs<\/h2>\n<p>\u00ab\u00a0Candidozyma auris est rare dans la population g\u00e9n\u00e9rale mais constitue une menace mortelle pour les patients des unit\u00e9s de soins intensifs\u00a0\u00bb, a d\u00e9clar\u00e9 l&rsquo;auteur principal Hugh Gifford de l&rsquo;Universit\u00e9 d&rsquo;Exeter.<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a23140\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>L&rsquo;agent pathog\u00e8ne adh\u00e8re \u00e0 la peau du patient et aux appareils environnants, il peut se transmettre d&rsquo;une personne \u00e0 l&rsquo;autre et est incroyablement difficile \u00e0 \u00e9liminer. \u00ab\u00a0Si l&rsquo;infection p\u00e9n\u00e8tre dans le sang d&rsquo;un patient affaibli, le taux de mortalit\u00e9 est de 45 pour cent.\u00a0\u00bb Les \u00e9pid\u00e9mies dans les unit\u00e9s de soins intensifs sont \u00e9galement co\u00fbteuses pour les h\u00f4pitaux et provoquent d\u2019importantes perturbations.<\/p>\n<\/div>\n<aside data-hk=\"0000a124212000a2315004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-mobile Ad-Slot-out\">\n<div id=\"ad-slot-mobile-out-1\" data-orientation=\"out\" data-index=\"1\" data-slot=\"ad-slot\" data-device=\"mobile\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\"><\/div>\n<\/aside>\n<div data-hk=\"0000a124212000a23160\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<h2>R\u00e9sistance aux m\u00e9dicaments dans les infections \u00e0 Candidozyma<\/h2>\n<p>L&rsquo;\u00e9quipe de Gifford a \u00e9tudi\u00e9 pourquoi deux patients gravement malades ne pouvaient pas \u00eatre gu\u00e9ris malgr\u00e9 un traitement \u00e0 l&rsquo;\u00e9chinocandine. Les \u00e9chinocandines sont une classe de m\u00e9dicaments qui attaquent la paroi cellulaire du champignon et sont consid\u00e9r\u00e9es comme le m\u00e9dicament de premi\u00e8re intention contre ces infections \u00e0 Candidozyma.<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a23170\" class=\"Ad-Carousel mb-xl row \" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\">\n<div data-hk=\"0000a124212000a231710\" class=\"col-lg-4\">\n<div data-hk=\"0000a124212000a231711004\" data-qa-ad-slot=\"https:\/\/www.focus.de\/gesundheit\/news\/true\" class=\"Ad-Slot Ad-Slot-desktop Ad-Slot-ver \" role=\"region\" aria-label=\"Anzeige 1\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\">\n<div id=\"ad-slot-desktop-ver-1\" data-orientation=\"ver\" data-index=\"1\" data-slot=\"ad-slot\" data-device=\"desktop\"><\/div>\n<\/div>\n<\/div>\n<div data-hk=\"0000a124212000a231712\" class=\"col-lg-4\">\n<aside data-hk=\"0000a124212000a231713004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-desktop Ad-Slot-ver Ad-Slot-FC\">\n<div class=\"Ad-Slot-FC-Container \" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\">\n<div class=\"Ad-Slot-FC-Window\">\n<div id=\"ad-slot-desktop-ver-2\" data-orientation=\"ver\" data-index=\"2\" data-slot=\"ad-slot\" data-device=\"desktop\"><\/div>\n<\/div>\n<\/div>\n<\/aside>\n<\/div>\n<div data-hk=\"0000a124212000a231714\" class=\"col-lg-4\">\n<div data-hk=\"0000a124212000a231715004\" data-qa-ad-slot=\"https:\/\/www.focus.de\/gesundheit\/news\/true\" class=\"Ad-Slot Ad-Slot-desktop Ad-Slot-ver \" role=\"region\" aria-label=\"Anzeige 3\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\">\n<div id=\"ad-slot-desktop-ver-3\" data-orientation=\"ver\" data-index=\"3\" data-slot=\"ad-slot\" data-device=\"desktop\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div data-hk=\"0000a124212000a23180\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>Jusqu&rsquo;\u00e0 pr\u00e9sent, la r\u00e9sistance \u00e0 ces m\u00e9dicaments a \u00e9t\u00e9 principalement associ\u00e9e \u00e0 des modifications des g\u00e8nes FKS1 et FKS2, mais les chercheurs n&rsquo;ont pas trouv\u00e9 de tels changements dans les cas examin\u00e9s.<\/p>\n<\/div>\n<aside data-hk=\"0000a124212000a2319004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-mobile Ad-Slot-hor\">\n<div id=\"ad-slot-mobile-hor-3\" data-orientation=\"hor\" data-index=\"3\" data-slot=\"ad-slot\" data-device=\"mobile\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\"><\/div>\n<\/aside>\n<div data-hk=\"0000a124212000a231a100\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<h2>Les chercheurs ont d\u00e9couvert un effet gr\u00e2ce \u00e0 un petit probl\u00e8me<\/h2>\n<p>Au cours des analyses, le hasard est venu \u00e0 la rescousse : un chercheur a accidentellement cultiv\u00e9 des plaques contenant Candidozyma auris et l&rsquo;antimycotique anidulafungine &#8211; un m\u00e9dicament utilis\u00e9 pour traiter les infections fongiques &#8211; pendant plus longtemps que pr\u00e9vu, a-t-on d\u00e9clar\u00e9.<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a231a110\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>Ce n\u2019est qu\u2019\u00e0 ce moment-l\u00e0 qu\u2019il est devenu \u00e9vident qu\u2019une infime partie des cellules avait continu\u00e9 \u00e0 cro\u00eetre pendant plusieurs jours. Une culture plus longue a \u00e9galement abouti \u00e0 deux formes de colonies significativement diff\u00e9rentes : des variantes petites et grandes. Les petits ont grandi plus lentement, les plus grands ont grandi plus vite.<\/p>\n<\/div>\n<aside data-hk=\"0000a124212000a231a12004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-mobile Ad-Slot-hor\">\n<div id=\"ad-slot-mobile-hor-4\" data-orientation=\"hor\" data-index=\"4\" data-slot=\"ad-slot\" data-device=\"mobile\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\"><\/div>\n<\/aside>\n<div data-hk=\"0000a124212000a231a130\" class=\"mb-lg\">\n<div data-hk=\"0000a124212000a231a1312\" data-qa-article-image class=\"Article-Image\">\n<figure data-hk=\"0000a124212000a231a131300\" class=\"Article-Content-Figure\"><!--$--><!--\/--><!--$--><\/p>\n<div data-hk=\"0000a124212000a231a1313020000\" class=\"Image-Container\" data-qa-image-container><\/div>\n<p><!--\/--><!--$--><figcaption data-hk=\"0000a124212000a231a1313030\" class=\"Article-Content-Figcaption\"><span data-hk=\"0000a124212000a231a131000\" data-qa-image-caption class=\"Image-Caption\"> <!--$-->La croissance des cellules est visible dans la bo\u00eete de P\u00e9tri.<!--\/--> <\/span><span data-hk=\"0000a124212000a231a131100\" data-qa-image-credit class=\"Image-Credit\"> <!--$-->Universit\u00e9 d&rsquo;Exeter<!--\/--> <!--$--><!--\/--><\/span><\/figcaption><!--\/--><\/figure>\n<\/div>\n<\/div>\n<div data-hk=\"0000a124212000a231a140\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<h2>Le champignon fait des copies de son g\u00e9nome et augmente les risques de mutations<\/h2>\n<p>Des tests ont montr\u00e9 que le champignon mortel avait surv\u00e9cu au traitement avec des m\u00e9dicaments antifongiques en r\u00e9alisant des copies suppl\u00e9mentaires de l&rsquo;int\u00e9gralit\u00e9 de son g\u00e9nome. Cela augmentait ses chances de muter pour \u00e9chapper \u00e0 la drogue et survivre. Les cellules \u00e0 croissance plus rapide des plus grandes colonies fongiques portaient beaucoup plus de mutations dans le g\u00e8ne CRZ1 que les isolats originaux et les petites variantes.<\/p>\n<\/div>\n<aside data-hk=\"0000a124212000a231a15004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-mobile Ad-Slot-hor\">\n<div id=\"ad-slot-mobile-hor-5\" data-orientation=\"hor\" data-index=\"5\" data-slot=\"ad-slot\" data-device=\"mobile\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\"><\/div>\n<\/aside>\n<div data-hk=\"0000a124212000a231a160\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>CRZ1 est associ\u00e9 \u00e0 la stabilit\u00e9 et au remodelage de la paroi cellulaire. D&rsquo;autres tests ont sugg\u00e9r\u00e9 que la r\u00e9ponse de la paroi cellulaire des cellules \u00e0 croissance rapide aux m\u00e9dicaments antifongiques \u00e9tait alt\u00e9r\u00e9e.<\/p>\n<\/div>\n<aside data-hk=\"0000a124212000a231a17004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-desktop Ad-Slot-hor Ad-Slot-FC\">\n<div class=\"Ad-Slot-FC-Container \" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\">\n<div class=\"Ad-Slot-FC-Window\">\n<div id=\"ad-slot-desktop-hor-2\" data-orientation=\"hor\" data-index=\"2\" data-slot=\"ad-slot\" data-device=\"desktop\"><\/div>\n<\/div>\n<\/div>\n<\/aside>\n<div data-hk=\"0000a124212000a231a180\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<h2>Candidozyma auris d\u00e9veloppe progressivement une r\u00e9sistance<\/h2>\n<p>Les chercheurs consid\u00e8rent ces r\u00e9sultats comme une indication que la r\u00e9sistance ne peut pas se d\u00e9velopper soudainement, mais plut\u00f4t progressivement : d&rsquo;abord plus de tol\u00e9rance, puis d&rsquo;autres changements g\u00e9n\u00e9tiques et enfin une r\u00e9sistance plus prononc\u00e9e.<\/p>\n<\/div>\n<aside data-hk=\"0000a124212000a231a19004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-mobile Ad-Slot-hor\">\n<div id=\"ad-slot-mobile-hor-6\" data-orientation=\"hor\" data-index=\"6\" data-slot=\"ad-slot\" data-device=\"mobile\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\"><\/div>\n<\/aside>\n<div data-hk=\"0000a124212000a231a200\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>\u00ab\u00a0Notre d\u00e9couverte signifie que nous devons d\u00e9sormais rechercher de nouvelles fa\u00e7ons de traiter les patients et \u00e9liminer ce champignon mortel des h\u00f4pitaux\u00a0\u00bb, concluent les chercheurs. Vous souhaitez maintenant examiner diverses options, comme l&rsquo;utilisation combin\u00e9e de diff\u00e9rents agents antifongiques.<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a231a210\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<h2>Le champignon est une menace mondiale pour la sant\u00e9 publique<\/h2>\n<p>Candidozyma auris \u2013 anciennement appel\u00e9 Candida auris \u2013 a \u00e9t\u00e9 d\u00e9crit pour la premi\u00e8re fois au Japon en 2009, mais son origine reste un myst\u00e8re. Depuis son apparition, des \u00e9pid\u00e9mies ont \u00e9t\u00e9 signal\u00e9es sur tous les continents, totalisant plus de 60 pays.<\/p>\n<\/div>\n<aside data-hk=\"0000a124212000a231a22004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-mobile Ad-Slot-hor\">\n<div id=\"ad-slot-mobile-hor-7\" data-orientation=\"hor\" data-index=\"7\" data-slot=\"ad-slot\" data-device=\"mobile\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\"><\/div>\n<\/aside>\n<div data-hk=\"0000a124212000a231a230\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>Il a \u00e9t\u00e9 class\u00e9 comme une menace mondiale pour la sant\u00e9 publique et figure sur la liste des agents pathog\u00e8nes fongiques prioritaires de l&rsquo;Organisation mondiale de la sant\u00e9 (OMS).<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a231a240\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<h2>L&rsquo;Allemagne enregistre le plus grand nombre de cas d&rsquo;infection<\/h2>\n<p>Selon les donn\u00e9es de l&rsquo;autorit\u00e9 sanitaire europ\u00e9enne ECDC, l&rsquo;Allemagne est l&rsquo;un des pays de l&rsquo;UE avec le plus de cas signal\u00e9s. \u00c0 l&rsquo;heure actuelle, le nombre de d\u00e9tections initiales de Candidozyma auris par an est relativement stable, autour de 100, a d\u00e9clar\u00e9 Oliver Kurzai, directeur de l&rsquo;Institut d&rsquo;hygi\u00e8ne et de microbiologie de l&rsquo;Universit\u00e9 de W\u00fcrzburg, qui n&rsquo;a pas particip\u00e9 \u00e0 l&rsquo;\u00e9tude britannique.<\/p>\n<\/div>\n<aside data-hk=\"0000a124212000a231a25004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-mobile Ad-Slot-hor\">\n<div id=\"ad-slot-mobile-hor-8\" data-orientation=\"hor\" data-index=\"8\" data-slot=\"ad-slot\" data-device=\"mobile\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\"><\/div>\n<\/aside>\n<aside data-hk=\"0000a124212000a231a26004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-desktop Ad-Slot-out\">\n<div id=\"ad-slot-desktop-out-1\" data-orientation=\"out\" data-index=\"1\" data-slot=\"ad-slot\" data-device=\"desktop\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\"><\/div>\n<\/aside>\n<div data-hk=\"0000a124212000a231a270\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>Il y a toujours des \u00e9pid\u00e9mies et \u00e0 mesure que l&rsquo;agent pathog\u00e8ne se propage, en particulier dans le sud de l&rsquo;Europe, la probabilit\u00e9 d&rsquo;une augmentation des importations augmente.<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a231a280\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<h2>\u00ab Nous craignons que le nombre de cas augmente dans les prochaines ann\u00e9es \u00bb<\/h2>\n<p>\u00ab\u00a0Il faut donc craindre que le nombre de cas augmente dans les prochaines ann\u00e9es\u00a0\u00bb, explique Kurzai, qui dirige le Centre national de r\u00e9f\u00e9rence des infections fongiques invasives (NRZMyk).<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a231a290\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>En Allemagne, il existe d\u00e9sormais une obligation de d\u00e9claration des preuves. La r\u00e9sistance \u00e0 l&rsquo;\u00e9chinocandine est actuellement rare dans ce pays ; on le trouve dans moins de cinq pour cent des souches de C. auris d\u00e9tect\u00e9es.<\/p>\n<\/div>\n<aside data-hk=\"0000a124212000a231a30004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-mobile Ad-Slot-hor\">\n<div id=\"ad-slot-mobile-hor-9\" data-orientation=\"hor\" data-index=\"9\" data-slot=\"ad-slot\" data-device=\"mobile\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\"><\/div>\n<\/aside>\n<div data-hk=\"0000a124212000a231a310\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<h2>\u00c9tats-Unis : une infection par un autre champignon provoque des abc\u00e8s c\u00e9r\u00e9braux<\/h2>\n<p>Aux USA, le d\u00e9veloppement d&rsquo;un autre champignon dangereux suscite d\u00e9j\u00e0 des inqui\u00e9tudes : Cladophialophora bantiana. Les infections par ce virus sont mortelles dans 60 \u00e0 70 pour cent des cas, selon l&rsquo;autorit\u00e9 sanitaire am\u00e9ricaine CDC.<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a231a320\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>Le nombre de d\u00e9tections dans un laboratoire clinique de r\u00e9f\u00e9rence a \u00e9t\u00e9 multipli\u00e9 par quatre entre 2023 et 2025, \u00e0 un faible niveau. \u00abLes raisons de cette augmentation apparente sont inconnues.\u00bb<\/p>\n<\/div>\n<aside data-hk=\"0000a124212000a231a33004\" data-qa-ad-slot class=\"Ad-Slot Ad-Slot-mobile Ad-Slot-hor\">\n<div id=\"ad-slot-mobile-hor-10\" data-orientation=\"hor\" data-index=\"10\" data-slot=\"ad-slot\" data-device=\"mobile\" data-nosnippet=\"https:\/\/www.focus.de\/gesundheit\/news\/true\"><\/div>\n<\/aside>\n<div data-hk=\"0000a124212000a231a340\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>En r\u00e8gle g\u00e9n\u00e9rale, la moisissure provoque des abc\u00e8s c\u00e9r\u00e9braux, selon l&rsquo;Institut Robert Koch (RKI). Les infections caus\u00e9es par Cladophialophora bantiana se produisent dans le monde entier. Les personnes \u00e2g\u00e9es de 50 ans et plus sont les plus touch\u00e9es. En Allemagne, les infections par ce champignon sont encore rares, a d\u00e9clar\u00e9 Kurzai. Il n\u2019existe actuellement aucun enregistrement syst\u00e9matique.<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a231a350\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<h2>Th\u00e8se\u00a0:\u00a0Le changement climatique facilite la propagation des moisissures<\/h2>\n<p>Les causes possibles de l\u2019augmentation du nombre d\u2019infections fongiques sont diverses, l\u2019un des facteurs \u00e9tant l\u2019am\u00e9lioration des options de diagnostic. Un lien avec le changement climatique est plausible, notamment avec le r\u00e9chauffement et les longues p\u00e9riodes de s\u00e9cheresse et de s\u00e9cheresse.<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a231a360\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p>\u00ab\u00a0Ces moisissures peuvent se propager plus facilement, car les spores sont transport\u00e9es dans l&rsquo;air avec la poussi\u00e8re et la terre.\u00a0\u00bb Jusqu\u2019\u00e0 pr\u00e9sent, ce n\u2019est qu\u2019une hypoth\u00e8se ; il n&rsquo;y a pas encore de preuve directe.<\/p>\n<\/div>\n<div data-hk=\"0000a124212000a231a370\" class=\"Html-Block\" data-qa-article-content-text data-text-milestone-block>\n<p><i>dpa<\/i><\/p>\n<\/div>\n<p><!--\/--><br \/>\n<!--$--><br \/>\n<!--\/--><br \/>\n<!--$--><br \/>\n<!--\/--><br \/>\n<!--$--><br \/>\n<!--\/--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Un m\u00e9canisme sp\u00e9cial aide le champignon hospitalier mortel Candidozyma auris \u00e0 \u00e9chapper au traitement. Un<\/p>\n","protected":false},"author":1,"featured_media":20560,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86],"tags":[171,2601,11153,1617,999,3627,3209,1162],"class_list":["post-20559","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-les-maladies","tag-aux","tag-champignons","tag-crazy","tag-gene","tag-hospitaliers","tag-mortels","tag-rend","tag-resistant","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50","resize-featured-image"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Le g\u00e8ne \u00ab Crazy One \u00bb rend r\u00e9sistant aux champignons hospitaliers mortels - RVH-Synergie.org<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rvh-synergie.org\/actualites\/le-gene-crazy-one-rend-resistant-aux-champignons-hospitaliers-mortels\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Le g\u00e8ne \u00ab Crazy One \u00bb rend r\u00e9sistant aux champignons hospitaliers mortels - RVH-Synergie.org\" \/>\n<meta property=\"og:description\" content=\"Un m\u00e9canisme sp\u00e9cial aide le champignon hospitalier mortel Candidozyma auris \u00e0 \u00e9chapper au traitement. 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