{"id":11286,"date":"2025-11-03T19:34:11","date_gmt":"2025-11-03T18:34:11","guid":{"rendered":"https:\/\/rvh-synergie.org\/actualites\/les-neurones-lies-a-la-recompense-conduisent-differemment-la-prise-de-decision-risquee-chez-les-rats-males-et-femelles\/"},"modified":"2025-11-03T19:34:14","modified_gmt":"2025-11-03T18:34:14","slug":"les-neurones-lies-a-la-recompense-conduisent-differemment-la-prise-de-decision-risquee-chez-les-rats-males-et-femelles","status":"publish","type":"post","link":"https:\/\/rvh-synergie.org\/actualites\/les-neurones-lies-a-la-recompense-conduisent-differemment-la-prise-de-decision-risquee-chez-les-rats-males-et-femelles\/","title":{"rendered":"Les neurones li\u00e9s \u00e0 la r\u00e9compense conduisent diff\u00e9remment la prise de d\u00e9cision risqu\u00e9e chez les rats m\u00e2les et femelles"},"content":{"rendered":"
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Certaines personnes souffrant de troubles psychiatriques, notamment de toxicomanie et de trouble d\u2019hyperactivit\u00e9 avec d\u00e9ficit de l\u2019attention, ont du mal \u00e0 contr\u00f4ler leurs pulsions ou \u00e0 prendre des d\u00e9cisions dans l\u2019incertitude. Dans le cadre d’une collaboration entre l’Universit\u00e9 de Cambridge et l’Universit\u00e9 de la Colombie-Britannique, Tristan Hynes et ses coll\u00e8gues ont utilis\u00e9 des rats pour explorer le r\u00f4le d’une population sp\u00e9cifique de neurones li\u00e9s \u00e0 la r\u00e9compense dans la formation de l’impulsivit\u00e9 et de la prise de d\u00e9cision risqu\u00e9e lors d’une t\u00e2che de jeu.<\/p>\n

Comme indiqu\u00e9 dans leur JNeurosci<\/i> Dans cet article, les chercheurs ont manipul\u00e9 l’activit\u00e9 de la population neuronale alors que les rats choisissaient entre quatre trous associ\u00e9s \u00e0 diff\u00e9rentes probabilit\u00e9s de recevoir une r\u00e9compense ou une punition de temps mort. Influencer l’activit\u00e9 neuronale \u00e0 mesure que les rats apprenaient la t\u00e2che affectait diff\u00e9remment la prise de d\u00e9cision risqu\u00e9e chez les m\u00e2les et les femelles.<\/p>\n

Mais lorsque les chercheurs ont manipul\u00e9 l\u2019activit\u00e9 neuronale apr\u00e8s que les rats avaient d\u00e9j\u00e0 appris la t\u00e2che, cela a affect\u00e9 de mani\u00e8re s\u00e9lective l\u2019impulsivit\u00e9 motrice chez les deux sexes. En d\u2019autres termes, le m\u00eame circuit neuronal pilotait des aspects de comportement totalement diff\u00e9rents selon le moment et le sexe.<\/p>\n

Selon Hynes, \u00ab\u00a0ces r\u00e9sultats soulignent que les circuits neuronaux ne fonctionnent pas de mani\u00e8re isol\u00e9e ou uniforme entre les individus\u00a0; ils modifient leur influence en fonction du sexe et de l’exp\u00e9rience. Ainsi, une approche universelle de la pharmacoth\u00e9rapie ne suffira pas\u00a0: l’endroit o\u00f9 une personne est dans la progression de son trouble et son sexe biologique peuvent changer la fa\u00e7on dont les circuits c\u00e9r\u00e9braux sous-jacents r\u00e9agissent au traitement.\u00a0\u00bb<\/p>\n

<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

Certaines personnes souffrant de troubles psychiatriques, notamment de toxicomanie et de trouble d\u2019hyperactivit\u00e9 avec d\u00e9ficit<\/p>\n","protected":false},"author":1,"featured_media":11287,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[56,1684,854,3413,7482,49,172,7481,2168,3189,2734,1895,4087],"class_list":["post-11286","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-les-addictions","tag-chez","tag-conduisent","tag-decision","tag-differemment","tag-femelles","tag-les","tag-lies","tag-males","tag-neurones","tag-prise","tag-rats","tag-recompense","tag-risquee","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50","resize-featured-image"],"yoast_head":"\nLes neurones li\u00e9s \u00e0 la r\u00e9compense conduisent diff\u00e9remment la prise de d\u00e9cision risqu\u00e9e chez les rats m\u00e2les et femelles - RVH-Synergie.org<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rvh-synergie.org\/actualites\/les-neurones-lies-a-la-recompense-conduisent-differemment-la-prise-de-decision-risquee-chez-les-rats-males-et-femelles\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Les neurones li\u00e9s \u00e0 la r\u00e9compense conduisent diff\u00e9remment la prise de d\u00e9cision risqu\u00e9e chez les rats m\u00e2les et femelles - 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