{"id":11103,"date":"2025-10-28T20:18:34","date_gmt":"2025-10-28T19:18:34","guid":{"rendered":"https:\/\/rvh-synergie.org\/actualites\/explorer-la-sante-renale-des-personnes-agees-sous-langle-de-la-multimorbidite\/"},"modified":"2025-10-28T20:18:34","modified_gmt":"2025-10-28T19:18:34","slug":"explorer-la-sante-renale-des-personnes-agees-sous-langle-de-la-multimorbidite","status":"publish","type":"post","link":"https:\/\/rvh-synergie.org\/actualites\/explorer-la-sante-renale-des-personnes-agees-sous-langle-de-la-multimorbidite\/","title":{"rendered":"Explorer la sant\u00e9 r\u00e9nale des personnes \u00e2g\u00e9es sous l\u2019angle de la multimorbidit\u00e9"},"content":{"rendered":"
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Une nouvelle th\u00e8se de doctorat publi\u00e9e r\u00e9cemment par Giorgi Beridze du Karolinska Institutet met en lumi\u00e8re la relation entre la multimorbidit\u00e9 et la sant\u00e9 r\u00e9nale chez les personnes \u00e2g\u00e9es. La recherche explore la fa\u00e7on dont la fonction r\u00e9nale est v\u00e9rifi\u00e9e chez les personnes \u00e2g\u00e9es, comment les maladies chroniques se regroupent en mod\u00e8les et comment ces mod\u00e8les influencent la fonction r\u00e9nale et le risque de d\u00e9velopper une albuminurie, une condition marqu\u00e9e par la pr\u00e9sence de prot\u00e9ines dans l’urine, souvent un signe pr\u00e9coce de l\u00e9sions r\u00e9nales.<\/p>\n

Les travaux de Beridze s’appuient sur les donn\u00e9es de deux grandes cohortes su\u00e9doises, SNAC-K et SCREAM, pour \u00e9valuer les performances des \u00e9quations bas\u00e9es sur la cr\u00e9atinine couramment utilis\u00e9es pour estimer la fonction r\u00e9nale. Les r\u00e9sultats r\u00e9v\u00e8lent que plusieurs de ces \u00e9quations ont fourni des estimations divergentes du taux d\u2019estimation glom\u00e9rulaire chez les personnes \u00e2g\u00e9es, en particulier chez les personnes \u00e2g\u00e9es ayant une faible masse musculaire. Cela a des implications significatives tant pour la pratique clinique que pour la recherche, car des \u00e9valuations inexactes peuvent conduire \u00e0 un diagnostic erron\u00e9 ou \u00e0 un retard de traitement.<\/p>\n

La th\u00e8se identifie \u00e9galement des mod\u00e8les distincts de multimorbidit\u00e9 \u2013 des combinaisons de maladies chroniques \u2013 qui sont li\u00e9s \u00e0 divers risques de d\u00e9clin r\u00e9nal. Notamment, certains sch\u00e9mas non traditionnellement associ\u00e9s \u00e0 une maladie r\u00e9nale se sont r\u00e9v\u00e9l\u00e9s pr\u00e9dictifs de l’albuminurie, tandis que les clusters cardiom\u00e9taboliques ont montr\u00e9 une forte corr\u00e9lation avec une d\u00e9t\u00e9rioration acc\u00e9l\u00e9r\u00e9e de la fonction r\u00e9nale.<\/p>\n

Adaptation des \u00e9valuations de la fonction r\u00e9nale<\/h2>\n

Beridze souligne l’importance d’adapter les \u00e9valuations de la fonction r\u00e9nale aux r\u00e9alit\u00e9s physiologiques du vieillissement. \u00ab\u00a0Nos r\u00e9sultats soulignent la n\u00e9cessit\u00e9 d’approches plus nuanc\u00e9es pour \u00e9valuer la sant\u00e9 r\u00e9nale des personnes \u00e2g\u00e9es\u00a0\u00bb, dit-il. \u00ab\u00a0En reconnaissant des mod\u00e8les de maladies sp\u00e9cifiques, nous pouvons mieux identifier les personnes \u00e0 risque et mettre en \u0153uvre des strat\u00e9gies pr\u00e9ventives qui favorisent un vieillissement en meilleure sant\u00e9.\u00a0\u00bb<\/p>\n

Projets futurs<\/h2>\n

Actuellement chercheur postdoctoral au Centre de recherche sur le vieillissement du Karolinska Institutet, Beridze pr\u00e9voit de continuer \u00e0 \u00e9tudier l’interaction entre la multimorbidit\u00e9 et la sant\u00e9 r\u00e9nale, avec de futures \u00e9tudes explorant le r\u00f4le du r\u00e9gime alimentaire et d’autres facteurs li\u00e9s au mode de vie. Son engagement envers l\u2019enseignement et le mentorat reste \u00e9galement un \u00e9l\u00e9ment cl\u00e9 de son parcours acad\u00e9mique.<\/p>\n

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Une nouvelle th\u00e8se de doctorat publi\u00e9e r\u00e9cemment par Giorgi Beridze du Karolinska Institutet met en<\/p>\n","protected":false},"author":1,"featured_media":476,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86],"tags":[393,16,1502,7379,7380,100,249,212,623],"class_list":["post-11103","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-les-maladies","tag-agees","tag-des","tag-explorer","tag-langle","tag-multimorbidite","tag-personnes","tag-renale","tag-sante","tag-sous","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-50","resize-featured-image"],"yoast_head":"\nExplorer la sant\u00e9 r\u00e9nale des personnes \u00e2g\u00e9es sous l\u2019angle de la multimorbidit\u00e9 - RVH-Synergie.org<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rvh-synergie.org\/actualites\/explorer-la-sante-renale-des-personnes-agees-sous-langle-de-la-multimorbidite\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Explorer la sant\u00e9 r\u00e9nale des personnes \u00e2g\u00e9es sous l\u2019angle de la multimorbidit\u00e9 - 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